Regional Geology Annals of China is a comprehensive and integrated display of the regional geological survey. It gave summary and records of new information, new development and the activity theory in regional geological survey, mining exploration and the latest research results over the past 20 years. Then it needs the reasonable and reliable 1:500 000 spatial geological map database and geographical base maps database for the project. On the MapGIS platform, using relational, database model and unified system library, we designed several rules for the Regional Geology Annals of China. The design contains the name principles of the professional map database, the coding method of various elements, the contents and structure of attributes table and so on. Then we developed database management systems and a range of supported software. It not only improved the database construction efficiency and achieved the precise quality but also realized the functions of user access to the system, data sharing, data query and so on. China Regional Geology Annals series map spatial database has laid a foundation for the realization of "one geology database", and provided a valuable learning experience for the construction of geological map database.