Bashibulake uranium deposit, which located in the northwest fringe of Tarim basin in Xinjiang Uygur Autonomous Region, was considered to be closely related with oil-reduced fading alteration. However, the evidences about the oil-reduced fading alteration genesis mainly came from the geological and geochemical microscopic researches. In this paper, the enhancement processing of Quickbird high spatial resolution satellite remote sensing data was firstly made on the basis of analyzing the geological characteristics of uranium mineralizing fading alteration sandstone and the band feature of Quickbird data. Through above processing, the ability of Quickbird images to interpret the fading alteration sandstone was further promoted. Secondly, the features about shape, spatial distribution for oil-reduced fading alteration sandstone which exposed on the Bashibulake uranium ore area were analyzed using the enhanced Quickbird images. Analysis included the following three aspects. One was the general distribution for the fading alteration sandstone from the wide scale of the uranium ore area and its around area. The second was the shape feature and spatial distribution characteristics for the purple red sandstone, which was not under subjected of fading alteration, from the scale of the whole uranium mineralization district. The third was the shape and spatial expand feature for the grey yellow fading alteration sandstone that is located in the internal of a large unfading purple red sandstone from the more large scale of the east uranium ore area. Above results provided the macroscopic evidence from both positive and negative aspects to verify the uranium mineralizing fading sandstone was generated by the oil-reduced alteration, rather than the original sediment genesis. In the same time, the idea about whole spatial distribution of the fading alteration sandstone can provide important information for uranium prospect in the outer edge of Bashibulake uranium mineralization area. All above researches fully show the great application potential for Quickbird high spatial resolution satellite remote sensing data on uranium mineralization exploration.