High resolution remote sensing technology (including high spatial resolution and hyper-spectral resolution) is an important new technology in field of geological exploration since the new century. In order to present the application of high resolution remote sensing technology in geological field, the Quickbird high spatial resolution satellite remote sensing technology and CASI (Compact Airborne Spectrographic Imager)/SASI (Shortwave infrared Airborne Spectrographic Imager) airborne hyper-spectral remote sensing technology were used to mine the uranium exploration information in north fringe of Tarim Basin, Xingjiang, in this paper. In first part, the feature and processing method of Quickbird and CASI/SASI data were introduced. Especially, a new method called the reverse enhancement method of uranium mineralization bleached alteration was discussed. In second part, the application of Quickbird data in identifying and analyzing the sandstone-type uranium mineralization bleached alteration was illustrated. In this part, some bleached alteration information related with uranium mineralization in Baxhibulake uranium region in Tarim Basin were identified using Quickbird high resolution remote sensing datum, and their spatial distribution raw was also analyzed. In third part, the application to discover new uranium mineralization belt and evaluate the favorable target zone using Quickbird and CASI/SASI data comprehensively were presented. In this part, an uranium mineralization belt named Salamubulake in east of Keping uplift in the north fringe of Tarim Basin was discovered using Quickbird remote sensing technology, and some alteration adjacent in the belt were identified and analyzed. Furthermore, the mineral composition for those alterations were mapped using CASI/SASI high resolution remote sensing datum. Its uranium metallogenetic potential was evaluated, and the favorable areas for uranium exploration were predicted. At last, the field investigation was also introduced and some conclusion were made that high resolution remote sensing technology has been utilized in uranium exploration field fully, and good application effects was made. Therefore, the application potential of high resolution remote sensing technology to geological exploration is valuable in being mined in the future.